The temptation to enhance athletes’ performance with substances is great when fame, money, and national pride are involved. From the early days of professional sports, both human and animal athletes have tried to improve their strength and endurance with a range of steroids, hormones, and other drugs. Antidoping regulations established by every conceivable sport seek to ensure fairness on the playing field. Yet deception occurs widely, whether from state-sponsored doping regimens or individual efforts. In this collection of articles, readers will gain a nuanced view of the issues and people involved in the most pivotal news about doping in the sports world.